Karlsburg has been an internationally distinguished place for diabetes research and treatment since 1930. In combination with the telemedicine system TeleDIAB®, the Karlsburg Diabetes Management System KADIS®, which is the result of 30 years intensive research, supports physicians and patients in their daily efforts to optimize the glycemic control. The services offered by the Diabetes Service Center Karlsburg is ready for use in the ambulatory practice with a number of specialized applications for e.g. education, optimization of glycemic control, prevention and personalized decision support.